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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LONP1 All Species: 28.48
Human Site: S217 Identified Species: 41.78
UniProt: P36776 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36776 NP_004784.2 959 106489 S217 G H R R V H I S R Q L E V E P
Chimpanzee Pan troglodytes XP_001143873 959 106437 S217 G H R R V H I S R Q L E V E P
Rhesus Macaque Macaca mulatta XP_001088663 909 101136 S217 G H R R V H I S R Q L E V E P
Dog Lupus familis XP_854391 960 106631 S218 G H R R I H I S R Q L E V E L
Cat Felis silvestris
Mouse Mus musculus Q8CGK3 949 105824 S205 G H R R I H I S R Q L E V E P
Rat Rattus norvegicus Q924S5 950 105774 S205 G H R R I H I S R Q L E V E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506549 791 89382 F126 L A L E S E P F A Y Y P N E V
Chicken Gallus gallus XP_001232112 790 89040 V125 E P E G K Q K V R R K Q K R P
Frog Xenopus laevis Q2TAF8 856 94553 A169 D N S V P A V A K L K R L L N
Zebra Danio Brachydanio rerio Q5PQY6 840 92202 L171 S V P V V A K L R R L L D S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649133 1006 112875 T186 A H R R I R I T G Q V V E D V
Honey Bee Apis mellifera XP_392970 995 112847 V205 A H R R I K I V G Q I L E E L
Nematode Worm Caenorhab. elegans O44952 971 108188 H177 L E L V L S A H R R I R A L E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P93648 964 105641 T194 G H R R L R I T E M V E E D P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93655 940 103912 L171 N E L K G K E L L N R L H E V
Baker's Yeast Sacchar. cerevisiae P36775 1133 127093 H275 M T A L L Y P H R R I K I D E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 86.6 93.7 N.A. 87.4 88.6 N.A. 71.6 73.8 32.2 32.7 N.A. 59.4 58.9 51.5 N.A.
Protein Similarity: 100 99.6 89 96 N.A. 92 92.8 N.A. 77 78.5 50.8 52.3 N.A. 73.3 74.9 67.2 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 6.6 13.3 0 20 N.A. 33.3 40 6.6 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 6.6 26.6 33.3 26.6 N.A. 60 53.3 26.6 N.A.
Percent
Protein Identity: N.A. 48.7 N.A. 48.1 39.1 N.A.
Protein Similarity: N.A. 65.8 N.A. 65.4 57.1 N.A.
P-Site Identity: N.A. 46.6 N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. 73.3 N.A. 13.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 7 7 0 0 13 7 7 7 0 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 0 0 0 7 19 0 % D
% Glu: 7 13 7 7 0 7 7 0 7 0 0 44 19 57 13 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 44 0 0 7 7 0 0 0 13 0 0 0 0 0 0 % G
% His: 0 57 0 0 0 38 0 13 0 0 0 0 7 0 0 % H
% Ile: 0 0 0 0 32 0 57 0 0 0 19 0 7 0 0 % I
% Lys: 0 0 0 7 7 13 13 0 7 0 13 7 7 0 0 % K
% Leu: 13 0 19 7 19 0 0 13 7 7 44 19 7 13 19 % L
% Met: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 7 7 0 0 0 0 0 0 0 7 0 0 7 0 7 % N
% Pro: 0 7 7 0 7 0 13 0 0 0 0 7 0 0 44 % P
% Gln: 0 0 0 0 0 7 0 0 0 50 0 7 0 0 0 % Q
% Arg: 0 0 57 57 0 13 0 0 63 25 7 13 0 7 0 % R
% Ser: 7 0 7 0 7 7 0 38 0 0 0 0 0 7 0 % S
% Thr: 0 7 0 0 0 0 0 13 0 0 0 0 0 0 0 % T
% Val: 0 7 0 19 25 0 7 13 0 0 13 7 38 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 7 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _